Amylin/DAP antibody

Catalog No. ABIN5691119

Product Details anti-Amylin/DAP Antibody

Target: Amylin/DAP (IAPP) (Islet Amyloid Polypeptide (IAPP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Amylin/DAP antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Isotype: Ig Mix

Application Details

Application Notes: Polyclonal anti-amylin is suitable for immunohistochemistry on frozen and paraffin-embedded tissues. Optimal antibody dilution should be determined by titration, recommended range is 1:800-1:1500 using PAP, or 1:300-1:500 using FITC, with over-night incubation at +4 °C.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 250 μL rabbit polyclonal antiserum containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C, or in small aliquots at -20°C.

Target Details for Amylin/DAP

Target: Amylin/DAP (IAPP) (Islet Amyloid Polypeptide (IAPP))

Alternative Name: Amylin (IAPP Products)

Synonyms: DAP antibody, IAP antibody, LOC100230121 antibody, Amylin antibody, islet amyloid polypeptide antibody, IAPP antibody, Iapp antibody

Background: Amylin or islet amyloid polypeptide (IAPP) is produced in the pancreas beta cells and co-released with insulin. The amino acid sequence shows great homology with calcitonin gene related peptide (CGRP). Amylin has been shown to reverse insulin inhibition of hepatic gluconeogenesis and to inhibit muscle uptake of glucose.

Polyclonal anti-Amylin was obtained by immunizing a rabbit with human amylin.

Pathways: Hormone Activity, Feeding Behaviour