POLL antibody (AA 307-407)

Catalog No. ABIN5692843

Product Details anti-POLL Antibody

Target: POLL (Polymerase (DNA Directed), lambda (POLL))

Binding Specificity: AA 307-407

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLL antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Brand: Picoband™

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for DNA Polymerase lambda detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.

Immunogen: E. coli-derived human DNA Polymerase lambda recombinant protein (Position: K307-N407).

Application Details

Application Notes:

Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Application Details: Western blot, 0.1-0.5 μg/mL
Direct ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Target Details for POLL

Target: POLL (Polymerase (DNA Directed), lambda (POLL))

Alternative Name: POLL (POLL Products)

Synonyms: T10O24.13 antibody, T10O24_13 antibody, zgc:66320 antibody, zgc:77901 antibody, wu:fe49a04 antibody, beta-n antibody, pol-kappa antibody, BETAN antibody, POLKAPPA antibody, 1110003P06Rik antibody, AV007317 antibody, DNA polymerase lambda (POLL) antibody, DNA polymerase lambda antibody, polymerase (DNA directed), lambda antibody, polymerase (DNA) lambda antibody, Pol{lambda} antibody, PTRG_00468 antibody, poll antibody, POLL antibody, MCYG_03796 antibody, LOC9325878 antibody, MGYG_02138 antibody, Poll antibody

Background:

Synonyms: DNA polymerase lambda , Pol Lambda

Tissue Specificity: Expressed in a number of tissues. Abundant in testis.

Background: DNA polymerase lambda, also known as POLL, is a protein found in eukaryotes. In humans, it is encoded by the POLLA gene. POLL has 5-prime-deoxyribose-5-phosphate lyase activity and strand-displacement synthesis activity on gapped DNA substrates, suggesting that POLL participates in short- and long-patch base excision repair. POLL is widely expressed, with abundant expression in pachytene spermatocytes of testis and in ovary.

Pathways: DNA Damage Repair, Production of Molecular Mediator of Immune Response