MUC7 antibody

Catalog No. ABIN5693028

Product Details anti-MUC7 Antibody

Target: MUC7 (Mucin 7, Secreted (MUC7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MUC7 antibody is un-conjugated

Application: Western Blotting (WB)

Brand: Picoband™

Sequence: QNKISRFLLY MKNLLNRIID DMVEQ

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for MUC7 detection. Tested with WB in Human.

Immunogen: A synthetic peptide corresponding to a sequence of human MUC7 (QNKISRFLLYMKNLLNRIIDDMVEQ).

Application Details

Application Notes:

Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Application Details: Western blot,0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Target Details for MUC7

Target: MUC7 (Mucin 7, Secreted (MUC7))

Alternative Name: MUC7 (MUC7 Products)

Synonyms: MG2 antibody, mucin 7, secreted antibody, mucin-7-like antibody, MUC7 antibody, LOC100625436 antibody

Background:

Synonyms: Mucin-7, MUC-7, Apo-MG2, Salivary mucin-7, MUC7, MG2

Tissue Specificity: Expressed in salivary gland tissues and only in those that contain mucous acinar cells (e.g. sublingual and submandibular glands) and not in salivary glands containing only serous acinar cells (e.g. parotid gland).

Background: Mucin-7 is a protein that in humans is encoded by the MUC7 gene. This gene encodes a small salivary mucin, which is thought to play a role in facilitating the clearance of bacteria in the oral cavity and to aid in mastication, speech, and swallowing. The central domain of this glycoprotein contains tandem repeats, each composed of 23 amino acids. This antimicrobial protein has antibacterial and antifungal activity. The most common allele contains 6 repeats, and some alleles may be associated with susceptibility to asthma. Alternatively spliced transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene.