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Glucosamine (N-Acetyl)-6-Sulfatase (GNS) (AA 238-355) antibody Primary Antibody

GNS Reactivity: Human, Mouse, Rat ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5693115
$240.00
Plus shipping costs $45.00
100 μg
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  • Target
    Glucosamine (N-Acetyl)-6-Sulfatase (GNS)
    Binding Specificity
    • 15
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 238-355
    Reactivity
    • 35
    • 8
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    Human, Mouse, Rat
    Host
    • 31
    • 3
    • 1
    Rabbit
    Clonality
    • 33
    • 2
    Polyclonal
    Conjugate
    • 21
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Un-conjugated
    Application
    • 18
    • 13
    • 13
    • 12
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    ELISA, Western Blotting (WB)
    Brand
    Picoband™
    Cross-Reactivity (Details)
    No cross reactivity with other proteins.
    Characteristics
    Rabbit IgG polyclonal antibody for GNS detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.
    Immunogen
    E. coli-derived human GNS recombinant protein (Position: W238-R355).
  • Application Notes

    Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

    Application Details: Western blot, 0.1-0.5 μg/mL
    Direct ELISA, 0.1-0.5 μg/mL

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Buffer
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
  • Target
    Glucosamine (N-Acetyl)-6-Sulfatase (GNS)
    Alternative Name
    GNS (GNS Antibody Abstract)
    Synonyms
    G6S, 2610016K11Rik, AU042285, C87209, N28088, NV14559, N-acetylglucosamine-6-sulfatase, zgc:114066, gns, wu:fi20h10, zgc:55370, glucosamine (N-acetyl)-6-sulfatase, glucosamine (N-acetyl)-6-sulfatase S homeolog, glucosamine (N-acetyl)-6-sulfatase a, N-acetylglucosamine-6-sulfatase, glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID), b, GNS, Gns, gns.S, gns, gnsa, CpipJ_CPIJ000745, Sros_7372, VDBG_04409, Halhy_3165, gnsb
    Background

    Synonyms: N-acetylglucosamine-6-sulfatase, Glucosamine-6-sulfatase, G6S, GNS

    Background: N-acetylglucosamine-6-sulfatase, also known as glucosamine (N-acetyl)-6-sulfatase, is an enzyme that in humans is encoded by the GNS gene. The product of this gene is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder mucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome.

    UniProt
    P15586
    Pathways
    Glycosaminoglycan Metabolic Process
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