eIF4EBP1 antibody

Catalog No. ABIN5696860

This Mouse Monoclonal antibody specifically detects eIF4EBP1 in WB, IHC and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for eIF4EBP1 antibody (ABIN5696860)

Target: eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This eIF4EBP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-eIF4EBP1 Antibody

Immunogen: eukaryotic translation initiation factor 4E binding protein 1

Isotype: IgG2b

Application Details

Application Notes: WB : 1:1000-1:10000,IHC : 1:20-1:200,IF : 1:20-1:200

Comment:

K-562 cells were subjected to SDS PAGE followed by western blot with FNab00006(4EBP1 antibody) at dilution of 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for eIF4EBP1

Target: eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))

Alternative Name: 4EBP1

Background: Synonyms:4E BP1, 4EBP1, BP 1, eIF4E binding protein 1, EIF4EBP1, PHAS I Background:Eukaryotic translation initiation factor 4E-binding protein 1(4EBP1), is a member of 4EBPs family, which regulate the translation of a subset of mRNA by competing with eIF4G for binding to eIF4E, thus preventing the assembly of the eIF4F complex. The eIF4F facilitates the recruitment of other translation initiation factors to form the complex and then initiates cap-dependent translation.4EBP1 also mediates the regulation of protein translation by growth factors, hormones and other stimuli that signal through the MAP kinase and mTORC1 pathways. There are three forms of 4EBP1, alpha, beta and gamma.

Molecular Weight: 12kDa

UniProt: Q13541

Pathways: MAPK Signaling, PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, Regulation of Cell Size, BCR Signaling