Exportin 7 antibody

Catalog No. ABIN5697657

Product Details anti-Exportin 7 Antibody

Target: Exportin 7 (XPO7)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Exportin 7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Immunogen: exportin 7

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:5000

Comment:

K-562 cells were subjected to SDS PAGE followed by western blot with FNab09551(XPO7 antibody) at dilution of 1:300

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for Exportin 7

Target: Exportin 7 (XPO7)

Alternative Name: XPO7 (XPO7 Products)

Synonyms: EXP7 antibody, RANBP16 antibody, exportin-7 antibody, ranbp16 antibody, xpo7 antibody, xpo7-b antibody, MGC98303 antibody, Exportin-7 antibody, DKFZp469N246 antibody, 4930506C02Rik antibody, BB164534 antibody, Ranbp16 antibody, mKIAA0745 antibody, CG33180 antibody, CG9126 antibody, CG9136 antibody, Dmel\\CG33180 antibody, RanBP16 antibody, exportin 7 antibody, exportin 7 S homeolog antibody, exportin 7 L homeolog antibody, CG33180 gene product from transcript CG33180-RE antibody, XPO7 antibody, Xpo7 antibody, xpo7 antibody, xpo7.S antibody, xpo7.L antibody, Ranbp16 antibody

Background: Synonyms:Exp7, exportin 7, KIAA0745, Ran binding protein 16, RANBP16, XPO7 Background:Mediates the nuclear export of proteins(cargos) with broad substrate specificity. In the nucleus binds cooperatively to its cargo and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex(NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP(induced by RANBP1 and RANGAP1, respectively) cause release of the cargo from the export receptor. XPO7 then return to the nuclear compartment and mediate another round of transport. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP-and GDP-bound forms of Ran between the cytoplasm and nucleus.

Molecular Weight: 129kDa

Gene ID: 23039

UniProt: Q9UIA9