SQLE antibody

Catalog No. ABIN5698486

Product Details anti-SQLE Antibody

Target: SQLE (Squalene Epoxidase (SQLE))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SQLE antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Immunogen: squalene epoxidase

Isotype: IgG

Application Details

Application Notes: WB : 1:200-1:2000 IP : 1:200-1:1000 IHC : 1:20-1:200 IF : 1:20-1:200

Comment:

A549 cells were subjected to SDS PAGE followed by western blot with FNab08209(SQLE antibody) at dilution of 1:300

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for SQLE

Target: SQLE (Squalene Epoxidase (SQLE))

Alternative Name: SQLE (SQLE Products)

Synonyms: An03g03770 antibody, AO090701000685 antibody, AI323792 antibody, squalene epoxidase antibody, SQLE antibody, ANI_1_450034 antibody, AOR_1_1218114 antibody, CC1G_03987 antibody, BDBG_08449 antibody, MCYG_02365 antibody, TERG_05717 antibody, Sqle antibody

Background: Synonyms:ERG1, FLJ30795, SE, SM, SQLE, squalene epoxidase, Squalene monooxygenase Background:SQLE, also named as ERG1, SE and SM, belongs to the squalene monooxygenase family. It catalyzes the first oxygenation step in cholesterol synthesis, acting on squalene before cyclization into the basic steroid structure. SQLE may serve as a flux-controlling enzyme beyond 3-hydroxy-3-methylglutaryl-coenzyme A reductase(HMGR, considered as rate limiting). It is also posttranslationally regulated by cholesterol-dependent proteasomal degradation.(PMID:21356516) The MW of SQLE is about 64kd.

Molecular Weight: 50 kDa

Gene ID: 6713

UniProt: Q14534