RTEL1 antibody

Catalog No. ABIN5700041

Product Details anti-RTEL1 Antibody

Target: RTEL1 (Regulator of Telomere Elongation Helicase 1 (RTEL1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RTEL1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Immunogen: regulator of telomere elongation helicase 1

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for RTEL1

Target: RTEL1 (Regulator of Telomere Elongation Helicase 1 (RTEL1))

Alternative Name: RTEL1 (RTEL1 Products)

Synonyms: F18B13.3 antibody, F18B13_3 antibody, C20orf41 antibody, DKCB5 antibody, NHL antibody, RTEL antibody, bK3184A7.3 antibody, AI451565 antibody, AW540478 antibody, Rtel antibody, RGD1306721 antibody, zgc:113114 antibody, regulator of telomere elongation helicase 1 antibody, RAD3-like DNA-binding helicase protein antibody, RTEL1 antibody, rtel1 antibody, AT1G79950 antibody, LOC100286037 antibody, Rtel1 antibody

Background: Synonyms:C20orf41, KIAA1088, NHL Background:ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing(SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by counteracting telomeric G4-DNA structures, which together ensure the dynamics and stability of the telomere.

Gene ID: 51750

UniProt: Q9NZ71