HIVEP1 antibody

Catalog No. ABIN5700087

Product Details anti-HIVEP1 Antibody

Target: HIVEP1 (Human Immunodeficiency Virus Type I Enhancer Binding Protein 1 (HIVEP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HIVEP1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Immunogen: human immunodeficiency virus type I enhancer binding protein 1

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for HIVEP1

Target: HIVEP1 (Human Immunodeficiency Virus Type I Enhancer Binding Protein 1 (HIVEP1))

Alternative Name: HIVEP1 (HIVEP1 Products)

Synonyms: ZAS1 antibody, CIRIP antibody, MBP-1 antibody, ZNF40 antibody, CRYBP1 antibody, ZNF40A antibody, PRDII-BF1 antibody, Schnurri-1 antibody, Cryabp1 antibody, Shn1 antibody, xhivep1 antibody, schnurri antibody, si:dkey-184j23.2 antibody, si:dkey-31k9.2 antibody, human immunodeficiency virus type I enhancer binding protein 1 antibody, human immunodeficiency virus type I enhancer binding protein 1 S homeolog antibody, HIVEP1 antibody, Hivep1 antibody, hivep1.S antibody, hivep1 antibody

Background: Synonyms:ZNF40 Background:This protein specifically binds to the DNA sequence 5'-GGGACTTTCC-3' which is found in the enhancer elements of numerous viral promoters such as those of SV40, CMV, or HIV-1. In addition, related sequences are found in the enhancer elements of a number of cellular promoters, including those of the class I MHC, interleukin-2 receptor, and interferon-beta genes. It may act in T-cell activation. Involved in activating HIV-1 gene expression. Isoform 2 and isoform 3 also bind to the IPCS(IRF1 and p53 common sequence) DNA sequence in the promoter region of interferon regulatory factor 1 and p53 genes and are involved in transcription regulation of these genes. Isoform 2 does not activate HIV-1 gene expression. Isoform 2 and isoform 3 may be involved in apoptosis.

Gene ID: 3096

UniProt: P15822