CTF18 antibody

Catalog No. ABIN5700511

Product Details anti-CTF18 Antibody

Target: CTF18 (CHTF18) (CTF18, Chromosome Transmission Fidelity Factor 18 Homolog (CHTF18))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CTF18 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Immunogen: CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Y79 cells were subjected to SDS PAGE followed by western blot with FNab01701(CHTF18 antibody) at dilution of 1:300

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for CTF18

Target: CTF18 (CHTF18) (CTF18, Chromosome Transmission Fidelity Factor 18 Homolog (CHTF18))

Alternative Name: CHTF18 (CHTF18 Products)

Synonyms: CHTF18 antibody, zgc:113153 antibody, MGC81266 antibody, 6030457M03Rik antibody, CTF18 antibody, Chl12 antibody, C16orf41 antibody, C321D2.2 antibody, C321D2.3 antibody, C321D2.4 antibody, CHL12 antibody, Ctf18 antibody, RUVBL antibody, chromosome transmission fidelity factor 18 antibody, CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae) antibody, chromosome transmission fidelity factor 18 L homeolog antibody, chromosome transmission fidelity protein 18 homolog antibody, CTF18, chromosome transmission fidelity factor 18 antibody, Chtf18 antibody, CHTF18 antibody, chtf18 antibody, chtf18.L antibody, LOC726742 antibody, LOC100160476 antibody, LOC100433034 antibody, LOC100442428 antibody, LOC100632105 antibody, LOC100642927 antibody

Background: Synonyms:C16orf41, C321D2.2, C321D2.3, C321D2.4, CHL12, CHTF18, Ctf18, hCTF18, RUVBL Background:Chromosome cohesion factor involved in sister chromatid cohesion and fidelity of chromosome transmission. Component of one of the cell nuclear antigen loader complexes, CTF18-replication factor C(CTF18-RFC), which consists of CTF18, CTF8, DCC1, RFC2, RFC3, RFC4 and RFC5. The CTF18-RFC complex binds to single-stranded and primed DNAs and has weak ATPase activity that is stimulated by the presence of primed DNA, replication protein A(RPA) and by proliferating cell nuclear antigen(PCNA). The CTF18-RFC complex catalyzes the ATP-dependent loading of PCNA onto primed and gapped DNA. It also interacts with and stimulates DNA polymerase POLH.

Molecular Weight: 110 kDa

Gene ID: 63922

UniProt: Q8WVB6