SPPL2A antibody

Catalog No. ABIN5701295

Product Details anti-SPPL2A Antibody

Target: SPPL2A (Signal Peptide Peptidase-Like 2A (SPPL2A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPPL2A antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Immunogen: signal peptide peptidase-like 2A

Isotype: IgG

Application Details

Application Notes: WB : 1:200-1:2000 IHC : 1:20-1:200

Comment:

human colon tissue were subjected to SDS PAGE followed by western blot with FNab08191(SPPL2A antibody) at dilution of 1:500

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for SPPL2A

Target: SPPL2A (Signal Peptide Peptidase-Like 2A (SPPL2A))

Alternative Name: SPPL2A (SPPL2A Products)

Synonyms: RGD1563001 antibody, SPPL2A antibody, LOC453430 antibody, LOC100231183 antibody, IMP3 antibody, PSL2 antibody, 2010106G01Rik antibody, C130089K23Rik antibody, signal peptide peptidase-like 2A antibody, signal peptide peptidase like 2A antibody, Signal peptide peptidase-like 2A antibody, Sppl2a antibody, SPPL2A antibody, sppl2a antibody, psl2 antibody

Background: Synonyms: Background:SPPL2A(Signal peptide peptidase-like 2A) is also named as IMP3(Intramembrane protease 3), PSL2(Presenilin-like protein 2) and belongs to the peptidase A22B family. It is an aspartyl intramembrane protease, has been implicated in the proteolysis of TNF-alpha, Fas Ligand and Bri2 and endogenous signal-peptide-peptidase-like2A(SPPL2a) is localised in lysosomes/late endosomes(PMID:21896273).

Molecular Weight: 45 kDa,100 kDa

UniProt: Q8TCT8