XRCC4 antibody

Catalog No. ABIN5701438

This Rabbit Polyclonal antibody specifically detects XRCC4 in WB, ELISA, IHC and IP. It exhibits reactivity toward Human and Rat.

Quick Overview for XRCC4 antibody (ABIN5701438)

Target: XRCC4 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4 (XRCC4))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This XRCC4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-XRCC4 Antibody

Purpose: XRCC4 antibody

Immunogen: X-ray repair complementing defective repair in Chinese hamster cells 4

Isotype: IgG

Application Details

Application Notes: WB:1:1000-1:10000,IHC:1:20-1:200,IP:1:200-1:2000

Comment:

K-562 cells were subjected to SDS PAGE followed by western blot with FNab09554(XRCC4 antibody) at dilution of 1:1000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for XRCC4

Target: XRCC4 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4 (XRCC4))

Alternative Name: XRCC4

Background:

Synonyms: DNA repair protein XRCC4 (hXRCC4)|X-ray repair cross-complementing protein 4|Protein XRCC4, C-terminus (XRCC4/C)|XRCC4

Background: The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V(D)J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED). Alternative splicing generates several transcript variants.

Molecular Weight: 32kDa,Observed 40kDa

Gene ID: 7518

UniProt: Q13426

Pathways: DNA Damage Repair, Production of Molecular Mediator of Immune Response