XRCC4 antibody

Catalog No. ABIN7211178

The Mouse Monoclonal anti-XRCC4 antibody is suitable to detect XRCC4 in samples from Human. It has been validated for WB, IHC, IF and IP.

Quick Overview for XRCC4 antibody (ABIN7211178)

Target: XRCC4 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4 (XRCC4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This XRCC4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Product Details anti-XRCC4 Antibody

Purpose: Mouse Anti-XRCC4 Monoclonal Antibody

Specificity: The antibody detects endogenous XRCC4 proteins.

Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Immunogen: Synthetic Peptide

Isotype: IgG1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:2000,IP 1:200,IF 1:200,IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.5 % BSA, 0.02 % sodium azide as Preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for XRCC4

Target: XRCC4 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4 (XRCC4))

Alternative Name: XRCC4

Background: XRCC4, DNA repair protein XRCC4, X-ray repair cross-complementing protein 4X-ray repair cross complementing 4 encoded by XRCC4 functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. X-ray repair cross complementing 4 plays a role in both non-homologous end joining and the completion of V (D)J recombination. Mutations in XRCC4 can cause short stature, microcephaly, and endocrine dysfunction (SSMED). Alternative splicing generates several transcript variants.

Molecular Weight: 38kD

Gene ID: 7518

UniProt: Q13426

Pathways: DNA Damage Repair, Production of Molecular Mediator of Immune Response