TCTN1 antibody

Catalog No. ABIN5702553

Product Details anti-TCTN1 Antibody

Target: TCTN1 (Tectonic Family Member 1 (TCTN1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCTN1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Immunogen: tectonic family member 1

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

mouse embryo tissue were subjected to SDS PAGE followed by western blot with FNab08567(TCTN1 antibody) at dilution of 1:800

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for TCTN1

Target: TCTN1 (Tectonic Family Member 1 (TCTN1))

Alternative Name: TCTN1 (TCTN1 Products)

Synonyms: FLJ21127 antibody, JBTS13 antibody, TECT1 antibody, G730031O11Rik antibody, Tect1 antibody, RGD1566266 antibody, tectonic family member 1 antibody, tectonic family member 1 L homeolog antibody, TCTN1 antibody, tctn1.L antibody, tctn1 antibody, Tctn1 antibody

Background: Synonyms:TECT1 Background:Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Regulator of Hedgehog(Hh), required for both activation and inhibition of the Hh pathway in the patterning of the neural tube. During neural tube development, it is required for formation of the most ventral cell types and for full Hh pathway activation. Functions in Hh signal transduction to fully activate the pathway in the presence of high Hh levels and to repress the pathway in the absence of Hh signals. Modulates Hh signal transduction downstream of SMO and RAB23(By similarity).

Gene ID: 79600

UniProt: Q2MV58

Pathways: Tube Formation