CHST1 antibody

Catalog No. ABIN5702712

Product Details anti-CHST1 Antibody

Target: CHST1 (Carbohydrate (Keratan Sulfate Gal-6) Sulfotransferase 1 (CHST1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHST1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Immunogen: carbohydrate (keratan sulfate Gal-6) sulfotransferase 1

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for CHST1

Target: CHST1 (Carbohydrate (Keratan Sulfate Gal-6) Sulfotransferase 1 (CHST1))

Alternative Name: CHST1 (CHST1 Products)

Synonyms: C6ST antibody, GST-1 antibody, KS6ST antibody, KSGal6ST antibody, KSST antibody, sulfo1 antibody, 2610008E20Rik antibody, AW125896 antibody, Gst1 antibody, KSGAL6ST antibody, carbohydrate sulfotransferase 1 antibody, carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 antibody, CHST1 antibody, Chst1 antibody

Background: Synonyms: Background:Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate(PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of galactose(Gal) residues of keratan. Has a preference for sulfating keratan sulfate, but it also transfers sulfate to the unsulfated polymer. The sulfotransferase activity on sialyl LacNAc structures is much higher than the corresponding desialylated substrate, and only internal Gal residues are sulfated. May function in the sulfation of sialyl N-acetyllactosamine oligosaccharide chains attached to glycoproteins. Participates in biosynthesis of selectin ligands. Selectin ligands are present in high endothelial cells(HEVs) and play a central role in lymphocyte homing at sites of inflammation.

Molecular Weight: 48-55 kDa

Gene ID: 8534

UniProt: O43916

Pathways: Glycosaminoglycan Metabolic Process