CD81 antibody

Catalog No. ABIN5703404

Product Details anti-CD81 Antibody

Target: CD81

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD81 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Immunogen: CD81 molecule

Isotype: IgG

Application Details

Application Notes: IHC : 1:50-1:500

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

References for anti-CD81 antibody (ABIN5703404)

Visnovitz, Osteikoetxea, Sódar, Mihály, Lőrincz, Vukman, Tóth, Koncz, Székács, Horváth, Varga, Buzás: "An improved 96 well plate format lipid quantification assay for standardisation of experiments with extracellular vesicles." in: Journal of extracellular vesicles, Vol. 8, Issue 1, pp. 1565263, (2019) (PubMed).

Target Details for CD81

Target: CD81

Alternative Name: CD81 (CD81 Products)

Synonyms: Tapa-1 antibody, Tapa1 antibody, Tspan28 antibody, CVID6 antibody, S5.7 antibody, TAPA1 antibody, TSPAN28 antibody, CD81 molecule antibody, CD81 molecule b antibody, CD81 antigen antibody, Cd81 molecule antibody, CD81 antibody, cd81b antibody, Cd81 antibody

Background: Synonyms:CD81, CD81 antigen, CD81 Molecule, S5.7, TAPA1, Tetraspanin 28, Tspan 28, TSPAN28 Background:The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene.

Gene ID: 975

UniProt: P60033

Pathways: Inositol Metabolic Process, Hepatitis C