Pellino 1 antibody

Catalog No. ABIN5704214

Product Details anti-Pellino 1 Antibody

Target: Pellino 1 (PELI1) (Pellino E3 Ubiquitin Protein Ligase 1 (PELI1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Pellino 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Immunogen: pellino homolog 1 (Drosophila)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for Pellino 1

Target: Pellino 1 (PELI1) (Pellino E3 Ubiquitin Protein Ligase 1 (PELI1))

Alternative Name: PELI1 (PELI1 Products)

Synonyms: 2810468L03Rik antibody, A930031K15Rik antibody, AA409794 antibody, AI586297 antibody, D11Ertd676e antibody, peli1 antibody, peli1.L antibody, pellino1 antibody, xpellino1 antibody, wu:fd12d01 antibody, zgc:153297 antibody, pellino E3 ubiquitin protein ligase 1 antibody, pellino 1 antibody, pellino E3 ubiquitin protein ligase 1 S homeolog antibody, pellino E3 ubiquitin protein ligase 1b antibody, PELI1 antibody, Peli1 antibody, peli1.S antibody, peli1b antibody

Background: Synonyms:PRISM Background:E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates 'Lys-63'-linked polyubiquitination of IRAK1 allowing subsequent NF-kappa-B activation.

Gene ID: 57162

UniProt: Q96FA3

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades