RRAGB antibody

Catalog No. ABIN5704301

Product Details anti-RRAGB Antibody

Target: RRAGB (Ras-Related GTP Binding B (RRAGB))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RRAGB antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Immunogen: Ras-related GTP binding B

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

human testis tissue were subjected to SDS PAGE followed by western blot with FNab07488(RRAGB antibody) at dilution of 1:500

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for RRAGB

Target: RRAGB (Ras-Related GTP Binding B (RRAGB))

Alternative Name: RRAGB (RRAGB Products)

Synonyms: RAGB antibody, bA465E19.1 antibody, Ragb antibody, RRAGB antibody, Ras related GTP binding B antibody, Ras-related GTP binding B antibody, RRAGB antibody, RragB antibody, Rragb antibody

Background: Synonyms: Background:Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade. Forms heterodimeric Rag complexes with RRAGC or RRAGD and cycles between an inactive GDP-bound and an active GTP-bound form. In its active form participates to the relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. Involved in the RCC1/Ran-GTPase pathway.

Gene ID: 10325

UniProt: Q5VZM2