VAMP8 antibody

Catalog No. ABIN5704541

Product Details anti-VAMP8 Antibody

Target: VAMP8 (Vesicle-Associated Membrane Protein 8 (Endobrevin) (VAMP8))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VAMP8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Immunogen: vesicle-associated membrane protein 8 (endobrevin)

Isotype: IgG

Application Details

Application Notes: WB :1:200-1:1000

Comment:

HL-60 cells were subjected to SDS PAGE followed by western blot with FNab09365( VAMP8 Antibody) at dilution of 1:300

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for VAMP8

Target: VAMP8 (Vesicle-Associated Membrane Protein 8 (Endobrevin) (VAMP8))

Alternative Name: VAMP8 (VAMP8 Products)

Synonyms: vamp8 antibody, EDB antibody, VAMP-8 antibody, AU041171 antibody, Edb antibody, endobrevin antibody, wu:fa18d07 antibody, zgc:56588 antibody, vesicle associated membrane protein 8 antibody, vesicle-associated membrane protein 8 (endobrevin) antibody, vesicle-associated membrane protein 8 antibody, vamp8 antibody, VAMP8 antibody, Vamp8 antibody

Background: Synonyms:EDB, Endobrevin, VAMP 8, VAMP8 Background:SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. VAMP8 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane via its interaction with the STX17-SNAP29 binary t-SNARE complex(PubMed:23217709, PubMed:25686604). Also required for dense-granule secretion in platelets(PubMed:12130530). Plays also a role in regulated enzyme secretion in pancreatic acinar cells(By similarity). Involved in the abscission of the midbody during cell division, which leads to completely separate daughter cells(By similarity). Involved in the homotypic fusion of early and late endosomes(By similarity).

Molecular Weight: 20kDa,observed 20kDa,50kDa

Gene ID: 8673

UniProt: Q9BV40