ZCCHC6 antibody
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- Target See all ZCCHC6 Antibodies
- ZCCHC6 (Zinc Finger, CCHC Domain Containing 6 (ZCCHC6))
- Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ZCCHC6 antibody is un-conjugated
- Application
- Western Blotting (WB), Immunoprecipitation (IP), ELISA
- Immunogen
- zinc finger, CCHC domain containing 6
- Isotype
- IgG
- Top Product
- Discover our top product ZCCHC6 Primary Antibody
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- Application Notes
- WB : 1:500-1:5000,IP:1:500-1:5000
- Comment
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PC-3 cells were subjected to SDS PAGE followed by western blot with FNab09611( ZCCHC6 Antibody) at dilution of 1:1000
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze / thaw cycles.
- Storage
- -20 °C
- Expiry Date
- 12 months
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- Target
- ZCCHC6 (Zinc Finger, CCHC Domain Containing 6 (ZCCHC6))
- Alternative Name
- ZCCHC6 (ZCCHC6 Products)
- Synonyms
- PAPD6 antibody, 6030448M23Rik antibody, AA420405 antibody, zinc finger CCHC-type containing 6 antibody, zinc finger, CCHC domain containing 6 antibody, ZCCHC6 antibody, Zcchc6 antibody
- Background
- Synonyms:DKFZp666B142, DKFZp686C11112, DKFZp686F119, DKFZp686I1269, HS2, KIAA1711, PAPD6, Terminal uridylyltransferase 7, TUT7, TUTase 7, ZCCHC6 Background:Uridylyltransferase that mediates the terminal uridylation of mRNAs with short(less than 25 nucleotides) poly(A) tails, hence facilitating global mRNA decay(PubMed:19703396, PubMed:25480299). Involved in microRNA(miRNA)-induced gene silencing through uridylation of deadenylated miRNA targets(PubMed:25480299). Also acts as a suppressor of miRNA biogenesis by mediating the terminal uridylation of some miRNA precursors, including that of let-7(pre-let-7). Uridylated pre-let-7 RNA is not processed by Dicer and undergo degradation. Pre-let-7 uridylation is strongly enhanced in the presence of LIN28A(PubMed:22898984). Due to functional redundancy between ZCCHC6 and ZCCHC11, the identification of the specific role of each of these proteins is difficult.
- Molecular Weight
- 185kDa
- Gene ID
- 79670
- UniProt
- Q5VYS8
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