MZB1 antibody

Catalog No. ABIN5705368

Product Details anti-MZB1 Antibody

Target: MZB1 (Marginal Zone B and B1 Cell-Specific Protein (MZB1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MZB1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Western Blotting (WB)

Immunogen: hypothetical protein MGC29506

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Raji cells were subjected to SDS PAGE followed by western blot with FNab05530(MZB1 antibody) at dilution of 1:1000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for MZB1

Target: MZB1 (Marginal Zone B and B1 Cell-Specific Protein (MZB1))

Alternative Name: MZB1 (MZB1 Products)

Synonyms: PACAP antibody, pERp1 antibody, MEDA-7 antibody, Pacap antibody, RGD1310251 antibody, 2010001M09Rik antibody, AV064572 antibody, marginal zone B and B1 cell specific protein antibody, marginal zone B and B1 cell-specific protein antibody, marginal zone B and B1 cell-specific protein 1 antibody, MZB1 antibody, Mzb1 antibody

Background: Synonyms:hypothetical protein MGC29506, MZB1, PACAP, pERp1 Background:Associates with immunoglobulin M(IgM) heavy and light chains and promotes IgM assembly and secretion. May exert its effect by acting as a molecular chaperone or as an oxidoreductase as it displays a low level of oxidoreductase activity(By similarity). Isoform 2 may be involved in regulation of apoptosis. Helps to diversify peripheral B-cell functions by regulating Ca(2+) stores, antibody secretion and integrin activation. Acts as a hormone-regulated adipokine/proinflammatory cytokine that is implicated in causing chronic inflammation, affecting cellular expansion and blunting insulin response in adipocytes. May have a role in the onset of insulin resistance.

Molecular Weight: 19-21 kDa

Gene ID: 51237

UniProt: Q8WU39

Pathways: Production of Molecular Mediator of Immune Response