EXD1 antibody

Catalog No. ABIN5705615

Product Details anti-EXD1 Antibody

Target: EXD1 (Exonuclease 3'-5' Domain Containing 1 (EXD1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EXD1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA

Immunogen: exonuclease 3'-5' domain containing 1

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for EXD1

Target: EXD1 (Exonuclease 3'-5' Domain Containing 1 (EXD1))

Alternative Name: EXD1 (EXD1 Products)

Synonyms: EXDL1 antibody, Exdl1 antibody, RGD1561009 antibody, 4932702D22Rik antibody, exd1 antibody, exonuclease 3'-5' domain containing 1 antibody, EXD1 antibody, Exd1 antibody, exd1 antibody

Background: Synonyms:EXDL1 Background:RNA-binding component of the PET complex, a multiprotein complex required for the processing of piRNAs during spermatogenesis. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposable elements, preventing their mobilization, which is essential for the germline integrity(By similarity). The PET complex is required during the secondary piRNAs metabolic process for the PIWIL2 slicing-triggered loading of PIWIL4 piRNAs. In the PET complex, EXD1 probably acts as an RNA adapter. EXD1 is an inactive exonuclease(By similarity).

Molecular Weight: 36 kDa, 58 kDa, 75 kDa

Gene ID: 161829

UniProt: Q8NHP7