PIK3C3 antibody (C-Term)

Catalog No. ABIN5706807

Product Details anti-PIK3C3 Antibody

Target: PIK3C3 (Phosphoinositide-3-Kinase, Class 3 (PIK3C3))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIK3C3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Characteristics:

Synonyms: rabbit anti-PI3K typ3 III antibody, KIAA0981, PIP5K3, Phosphatidylinositol 3-phosphate 5-kinase type III, FYVE finger-containing phosphoinositide kinase, PIKfyve, 1-phosphatidylinositol 3-phosphate 5-kinase, Type III PIP kinase

Background: Phosphatidylinositol 3-phosphate 5-kinase type III is a member of PI3/PI4-kinase family, PI4KII alpha is widely expressed with the highest amount of expression in the kidney, brain, heart, skeletal muscle, and placenta. The protein endoced by this gene regulates endosomal sorting, mutations can cause fleck corneal dystrophy. Anti-PI3K type III antibody is ideal for investigators interested in Kinase and Phosphatase Antibodies.

Gene Name: PIKFYVE

Purification: Anti-PI3K, type III was affinity purified from monospecific antiserum by immunoaffinity chromatography. A BLAST analysis was used to suggest cross-reactivity with mouse and human based on 100% sequence homology. Cross-reactivity with PI3K, type III from other sources has not been determined.

Immunogen:

Immunogen: Anti-PI3K, type III affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the C-terminal region of human PI3K, type III protein.

Immunogen Type: Peptide

Isotype: IgG

Application Details

Application Notes:

Application Note: Anti-PI3K, type III antibody is useful for ELISA, Immunohistochemistry, and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~237  kDa corresponding to the appropriate cell lysate or extract.

Western Blot Dilution: 1 μg/mL

ELISA Dilution: 1: 10,000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.02 mg/mL

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride,  pH 7.2

Stabilizer: 50 % (v/v) Glycerol

Preservative: Without preservative

Storage: 4 °C,-20 °C

Expiry Date: 12 months

Target Details for PIK3C3

Target: PIK3C3 (Phosphoinositide-3-Kinase, Class 3 (PIK3C3))

Alternative Name: PI3K type III (PIK3C3 Products)

Synonyms: im:7147158 antibody, wu:fc13g06 antibody, wu:fz51e12 antibody, zgc:112016 antibody, zgc:113009 antibody, VPS34 antibody, hVps34 antibody, 5330434F23Rik antibody, Vps34 antibody, phosphatidylinositol 3-kinase catalytic subunit type 3 antibody, phosphatidylinositol 3-kinase catalytic subunit type 3 L homeolog antibody, phosphatidylinositol 3-kinase, catalytic subunit type 3 antibody, PIK3C3 antibody, pik3c3.L antibody, pik3c3 antibody, Pik3c3 antibody

UniProt: Q9Y2I7

Pathways: AMPK Signaling, Activation of Innate immune Response, Inositol Metabolic Process, Toll-Like Receptors Cascades, Autophagy