EPS15 antibody

Catalog No. ABIN5708353

Product Details anti-EPS15 Antibody

Target: EPS15 (Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPS15 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antigen affinity purified

Immunogen: A recombinant human protein corresponding to amino acids A2-E88 was used as the immunogen for the EPS15 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the EPS15 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL, Direct ELISA: 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the EPS15 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for EPS15

Target: EPS15 (Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15))

Alternative Name: EPS15 / Epidermal growth factor receptor substrate 15 (EPS15 Products)

Synonyms: AF-1P antibody, AF1P antibody, MLLT5 antibody, CG16932 antibody, Dmel\\CG16932 antibody, EH1 antibody, EPS-15 antibody, Eps15 antibody, anon-WO0118547.85 antibody, eps-15 antibody, eps15 antibody, i31 antibody, 2410112D09Rik antibody, RGD1307641 antibody, epidermal growth factor receptor pathway substrate 15 antibody, Epidermal growth factor receptor pathway substrate clone 15 antibody, hypothetical protein antibody, EPS15 antibody, Eps-15 antibody, eps15 antibody, Eps15 antibody, PGTG_06574 antibody

Background: Epidermal growth factor receptor substrate 15 is a protein that in humans is encoded by the EPS15 gene. This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

UniProt: P42566

Pathways: EGFR Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, EGFR Downregulation