NOXA antibody (Internal Region)

Catalog No. ABIN570949

This Goat Polyclonal antibody specifically detects NOXA in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for NOXA antibody (Internal Region) (ABIN570949)

Target: NOXA (PMAIP1) (Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This NOXA antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Grade: Verified

Product Details anti-NOXA Antibody

Binding Specificity: Internal Region

Purpose: NOXA

Sequence: TQLRRFGDKL NFRQK

Cross-Reactivity: Human

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogen: Peptide with sequence C-TQLRRFGDKLNFRQK, from the internal region of the protein sequence according to NP_066950.1.

Isotype: IgG

Application Details

Application Notes:

Western Blot: Approx 16 kDa band observed in Human Brain (Cerebellum) lysates (calculated MW of 6.03 kDa according to NP_066950.1). This molecular weight is routinely observed by other sources. Recommended concentration: 0.03-0.1 μg/mL.

Peptide ELISA: antibody detection limit dilution 1:16000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for NOXA

Target: NOXA (PMAIP1) (Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1))

Alternative Name: PMAIP1

Background: PMAIP1, phorbol-12-myristate-13-acetate-induced protein 1, APR, NOXA, adult T cell leukemia-derived PMA-responsive

Gene ID: 5366

NCBI Accession: NP_066950

Pathways: p53 Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus