GDF2 antibody (AA 87-98)

Catalog No. ABIN576108

This anti-GDF2 antibody is a Rabbit Polyclonal antibody detecting GDF2 in ELISA. Suitable for Human.

Quick Overview for GDF2 antibody (AA 87-98) (ABIN576108)

Target: GDF2 (Growth Differentiation Factor 2 (GDF2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GDF2 antibody is un-conjugated

Application: ELISA

Product Details anti-GDF2 Antibody

Binding Specificity: AA 87-98

Specificity: Recognizes Human BMP9 (Bone Morphogenic Protein), a member of the TGF-beta superfamily. BMPs act through binding with a receptor complex consisting of type I and type II serine/threonine kinases, resulting ultimately in the activation of the Smad protein and mitogen-activated protein kinase (MAPK) signaling pathways. Several antagonist proteins, including, noggin, chordin, gremlin and follistatin, are responsible for modulating the signaling effects of BMPs, through the binding and blocking of receptor ligands, thereby preventing activation.

Purification: Protein G purified

Immunogen: Synthetic peptide corresponding to the amino acids 87 - 98 of the native molecule conjugated to keyhole limpet hemocyanin.

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.2, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for GDF2

Target: GDF2 (Growth Differentiation Factor 2 (GDF2))

Alternative Name: GDF2 / BMP9

Background: Name/Gene ID: GDF2
Family: TGF beta

Synonyms: GDF2, BMP-9, BMP9, GDF-2, Bone morphogenetic protein 9

Gene ID: 2658

Pathways: Transition Metal Ion Homeostasis