Integrin beta 2 antibody (PE)

Catalog No. ABIN576466

This Mouse Monoclonal antibody specifically detects Integrin beta 2 in FACS. It exhibits reactivity toward Pig and Camel.

Quick Overview for Integrin beta 2 antibody (PE) (ABIN576466)

Target: Integrin beta 2 (ITGB2)

Reactivity: Pig, Camel

Host: Mouse

Clonality: Monoclonal

Conjugate: This Integrin beta 2 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-Integrin beta 2 Antibody (PE)

Specificity: Recognizes the porcine homologue of human CD18. Clone PNK-I immunoprecipitates molecules of 166, 155 and 95 kD under reducing and non-reducing conditions. Clone PNK-I has been reported to inhibit porcine NK activity without affecting antibody-dependent cellular cytotoxicity.

Purification: Protein G purified

Immunogen: Porcine large granular lymphocytes.

Type of Immunogen: Cells

Isotype: IgG1

Application Details

Application Notes: Approved: Flo (1:1)

Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Method sheets are available on request. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Pig

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled Water.

Concentration: Lot specific

Buffer: Lyophilized, PBS,  pH 7.4, 0.09 % sodium azide, 1 % BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for Integrin beta 2

Target: Integrin beta 2 (ITGB2)

Alternative Name: ITGB2 / MAC-1 / CD18

Background: Name/Gene ID: ITGB2
Family: Integrin

Synonyms: ITGB2, CD18 antigen, CD18, Integrin beta chain, beta 2, LCAMB, MAC-1, MFI7, MF17, Integrin beta-2, LAD, LFA-1

Gene ID: 3689

Pathways: NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation