Integrin Alpha2b antibody (PE)

Catalog No. ABIN576525

This anti-Integrin Alpha2b antibody is a Mouse Monoclonal antibody detecting Integrin Alpha2b in FACS. Suitable for Human, Baboon and Mink.

Quick Overview for Integrin Alpha2b antibody (PE) (ABIN576525)

Target: Integrin Alpha2b (CD41)

Reactivity: Human, Baboon, Mink

Host: Mouse

Clonality: Monoclonal

Conjugate: This Integrin Alpha2b antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-Integrin Alpha2b Antibody (PE)

Specificity: Recognizes the human CD41 cell surface antigen, a 140kD glycoprotein expressed by platelets and megakaryocytes. CD41 is also known as platelet glycoprotein IIb, and functions as a receptor for fibrinogen, fibronectin and vWF. It has not been established if clone Recognizes free CD41 or CD41 only when complexed with CD61. However, antibody binding is reduced in the presence of EDTA suggesting that the epitope recognized is dependent upon an intact CD41/61 complex.

Purification: Ion exchange chromatography

Immunogen: Human platelet plasma membrane.

Type of Immunogen: Membrane preparation

Isotype: IgG1

Application Details

Application Notes: Approved: Flo (1:1)

Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 100 μL whole blood. Method sheets are available on request. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute with 1 mL distilled water.

Concentration: Lot specific

Buffer: Lyophilized PBS, 0.09 % sodium azide, 1 % BSA, 5 % sucrose

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze. Product is photosensitive and should be protected from light. Store undiluted.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze. Protect from light. Store undiluted.

Target Details for Integrin Alpha2b

Target: Integrin Alpha2b (CD41)

Alternative Name: ITGA2B / CD41

Background: Name/Gene ID: ITGA2B
Family: Integrin

Synonyms: ITGA2B, BDPLT2, CD41B, GT, gp2B, Integrin alpha-IIb, ITGAB, GPIIb, HPA3, Platelet-specific antigen BAK, CD41, CD41 antigen, GPalpha IIb, GTA

Gene ID: 3674

UniProt: P08514

Pathways: Integrin Complex