TPMT antibody (AA 1-245)

Catalog No. ABIN5776128

This Mouse Monoclonal antibody specifically detects TPMT in WB, ELISA, IF and ICC. It exhibits reactivity toward Human.

Quick Overview for TPMT antibody (AA 1-245) (ABIN5776128)

Target: TPMT (Thiopurine S-Methyltransferase (TPMT))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TPMT antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: AT2E7

Product Details anti-TPMT Antibody

Binding Specificity: AA 1-245

Purpose: Human TPMT antibody

Purification: Purified

Immunogen: Recombinant human TPMT (1-245aa) purified from E. coli

Isotype: IgG1 kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing cycles

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for TPMT

Target: TPMT (Thiopurine S-Methyltransferase (TPMT))

Alternative Name: TPMT

Background: TPMT (Thiopurine S-methyltransferase) is a very important enzyme for the metabolizm of thiopurine compounds. TPMT pharmacogenetics has been studied extensively because of its clinical significance. Many patients got benefited from the knowledge of TPMT genotype-phenotype correlation. Also, TPMT activity exhibits autosomal codominant genetic polymorphism, and patients inheriting TPMT-deficiency are at high risk of potentially fatal hematopoietic toxicity.

NCBI Accession: NP_000358