Integrin Alpha7 LC (Cleaved-Glu959) antibody

Catalog No. ABIN5956401

Product Details

Target: Integrin Alpha7 LC

Binding Specificity: Cleaved-Glu959

Reactivity: Human, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: ELISA, Western Blotting (WB)

Specificity: Alpha 7,FLJ25220,Integrin alpha 7,Integrin alpha 7 chain,Integrin alpha 7 heavy chain,Integrin alpha 7 light chain,Integrin alpha-7 70 kDa form,ITA7,ITGA 7,Itga7

Purification: Affinity purification

Immunogen: Synthesized peptide derived from the C-terminal region of human Integrin alpha7 LC

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, ELISA 1:40000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details

Target: Integrin Alpha7 LC

Background: The protein encoded by this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. They mediate a wide spectrum of cell-cell and cell-matrix interactions, and thus play a role in cell migration, morphologic development, differentiation, and metastasis. This protein functions as a receptor for the basement membrane protein laminin-1. It is mainly expressed in skeletal and cardiac muscles and may be involved in differentiation and migration processes during myogenesis. Defects in this gene are associated with congenital myopathy. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Molecular Weight: 129kDa

Gene ID: 3679

UniProt: Q13683