FOXO1 antibody (Ser319)

Catalog No. ABIN5956566

The Rabbit Polyclonal anti-FOXO1 antibody has been validated for WB, ELISA, IF and IHC (p). It is suitable to detect FOXO1 in samples from Human, Mouse and Rat.

Quick Overview for FOXO1 antibody (Ser319) (ABIN5956566)

Target: FOXO1 (Forkhead Box O1 (FOXO1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXO1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-FOXO1 Antibody

Binding Specificity: Ser319

Specificity: FKH 1,FKH1,FKHR,Forkhead (Drosophila) homolog 1 (rhabdomyosarcoma),Forkhead box O1,Forkhead box protein O1,Forkhead box protein O1A,Forkhead in rhabdomyosarcoma,Forkhead,Drosophila,homolog of,in rhabdomyosarcoma,FoxO transcription factor,foxo1,FOXO1,FOXO1A,OTTHUMP00000018301

Purification: Affinity purification

Immunogen: Synthesized peptide derived from human FoxO1 around the non-phosphorylation site of Ser319.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FOXO1

Target: FOXO1 (Forkhead Box O1 (FOXO1))

Alternative Name: FOXO1

Background: Transcription factor which acts as a regulator of cell responses to oxidative stress. In the presence of KIRT1, mediates down-regulation of cyclin D1 and up-regulation of CDKN1B levels which are required for cell transition from proliferative growth to quiescence.

Molecular Weight: 70kDa

Gene ID: 2308

UniProt: Q12778

Pathways: PI3K-Akt Signaling, Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Carbohydrate Metabolic Process, CXCR4-mediated Signaling Events, BCR Signaling