FOXO1 antibody (Ser256)

Catalog No. ABIN5956567

This anti-FOXO1 antibody is a Rabbit Polyclonal antibody detecting FOXO1 in WB, ELISA, IF and IHC (p). Suitable for Human, Mouse and Rat.

Quick Overview for FOXO1 antibody (Ser256) (ABIN5956567)

Target: FOXO1 (Forkhead Box O1 (FOXO1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXO1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-FOXO1 Antibody

Binding Specificity: Ser256

Specificity: FKH 1,FKH1,FKHR,Forkhead (Drosophila) homolog 1 (rhabdomyosarcoma),Forkhead box O1,Forkhead box protein O1,Forkhead box protein O1A,Forkhead in rhabdomyosarcoma,Forkhead,Drosophila,homolog of,in rhabdomyosarcoma,FoxO transcription factor,foxo1,FOXO1,FOXO1A,OTTHUMP00000018301

Purification: Affinity purification

Immunogen: Synthesized peptide derived from human FoxO1 around the non-phosphorylation site of Ser256.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FOXO1

Target: FOXO1 (Forkhead Box O1 (FOXO1))

Alternative Name: FoxO1

Background: Transcription factor which acts as a regulator of cell responses to oxidative stress. In the presence of KIRT1, mediates down-regulation of cyclin D1 and up-regulation of CDKN1B levels which are required for cell transition from proliferative growth to quiescence.

Molecular Weight: 70kDa

Gene ID: 2308

UniProt: Q12778

Pathways: PI3K-Akt Signaling, Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Carbohydrate Metabolic Process, CXCR4-mediated Signaling Events, BCR Signaling