P57 antibody

Catalog No. ABIN5959792

Product Details

Target: P57

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB), ELISA

Specificity: Beckwith Wiedemann syndrome,BWCR,BWS,CDKI,CDKN 1C,CDKN1C,CDN1C,Cyclin dependent kinase inhibitor 1C,Cyclin dependent kinase inhibitor p57,Cyclin-dependent kinase inhibitor 1C,Cyclin-dependent kinase inhibitor p57,KIP 2,KIP2,p57,p57 Kip 2,p57KIP2,WBS

Purification: Affinity purification

Immunogen: Synthesized peptide derived from the N-terminal region of human p57

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide,0.5 % BSA and 50 % glycerol  pH 7.4.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details

Target: P57

Synonyms: Clabp antibody, Lmb3 antibody, TACO antibody, p57 antibody, CLABP antibody, CLIPINA antibody, HCORO1 antibody, coronin, actin binding protein 1A antibody, coronin 1A antibody, Coro1a antibody, CORO1A antibody

Background: Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non-proliferative state throughout life.

Molecular Weight: 32kDa

Gene ID: 1028

UniProt: P49918