ZFP36L1 antibody (Ser92)

Catalog No. ABIN5962382

Product Details anti-ZFP36L1 Antibody

Target: ZFP36L1 (ZFP36 Ring Finger Protein-Like 1 (ZFP36L1))

Binding Specificity: Ser92

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZFP36L1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Berg36,BRF1,Butyrate response factor 1,C3H1 type-like 1,cMG1,EGF-response factor 1,ERF-1,ERF1,Protein TIS11B,RNF162B,TIS11B,TISB,ZFP36L1,Zinc finger protein 36

Purification: Affinity purification

Immunogen: Synthesized peptide derived from human TIS11B around the non-phosphorylation site of S92.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide,0.5 % BSA and 50 % glycerol  pH 7.4.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ZFP36L1

Target: ZFP36L1 (ZFP36 Ring Finger Protein-Like 1 (ZFP36L1))

Alternative Name: TIS11B (ZFP36L1 Products)

Synonyms: ZFP36L1 antibody, berg36 antibody, brf1 antibody, c3h-2 antibody, cmg1 antibody, erf-1 antibody, erf1 antibody, rnf162b antibody, tis11b antibody, BRF1 antibody, Berg36 antibody, ERF-1 antibody, ERF1 antibody, RNF162B antibody, TIS11B antibody, cMG1 antibody, Brf1 antibody, TIS11b antibody, AW742437 antibody, AW743212 antibody, D530020L18Rik antibody, cb198 antibody, cb480 antibody, fk89d11 antibody, id:ibd1247 antibody, sb:cb198 antibody, sb:cb480 antibody, wu:fb80h11 antibody, wu:fb92f07 antibody, wu:fk89d11 antibody, zfp36l1 antibody, zfp36l2 antibody, zgc:153979 antibody, fc06f10 antibody, wu:fc06f10 antibody, zfp36l1l antibody, zgc:77882 antibody, ZFP36 ring finger protein-like 1 S homeolog antibody, ZFP36 ring finger protein like 1 antibody, zinc finger protein 36, C3H type-like 1 antibody, zinc finger protein 36, C3H type-like 1a antibody, BRF1, RNA polymerase III transcription initiation factor subunit antibody, transcription factor IIIB 90 kDa subunit antibody, zinc finger protein 36, C3H type-like 1b antibody, zfp36l1.S antibody, ZFP36L1 antibody, Zfp36l1 antibody, zfp36l1a antibody, BRF1 antibody, LOC100350146 antibody, zfp36l1b antibody

Background: This gene is a member of the TIS11 family of early response genes, which are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. This gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.ZFP36L1 (ZFP36 Ring Finger Protein Like 1) is a Protein Coding gene. Diseases associated with ZFP36L1 include Sotos Syndrome 1. Among its related pathways are Validated targets of C-MYC transcriptional repression and PI3K / Akt Signaling. GO annotations related to this gene include poly(A) RNA binding and mRNA binding. An important paralog of this gene is ZFP36L2.

Molecular Weight: 36kDa

Gene ID: 677

UniProt: Q07352