FcRn antibody

Catalog No. ABIN5963440

Product Details anti-FcRn Antibody

Target: FcRn (IgG receptor FcRn (FcRn))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FcRn antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human FCGRT

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FcRn

Target: FcRn (IgG receptor FcRn (FcRn))

Alternative Name: FCGRT (FcRn Products)

Synonyms: FCRN antibody, alpha-chain antibody, FcRn antibody, Fc fragment of IgG receptor and transporter antibody, Fc receptor, IgG, alpha chain transporter antibody, FCGRT antibody, Fcgrt antibody

Background:

Synonyms: Alpha chain,Fc fragment of IgG, receptor transporter, alpha,FCGRN,FCGRT,FcRn alpha chain,FcRn,FCRN, alpha chain,IgG Fc fragment receptor transporter alpha chain,IgG Gc receptor,IgG receptor FcRn large subunit p51,IgG receptor FcRn large subunit p51 precursor,Immunoglobulin receptor, intestinal, heavy chain,Neonatal Fc receptor

Background: This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants.

Molecular Weight:

Observed_MW: 55kDa

Calculated_MW: 39kDa

Gene ID: 2217

UniProt: P55899

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process