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BRE antibody

BRE Reactivity: Human, Mouse, Rat IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5963810
  • Target See all BRE Antibodies
    BRE (Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE))
    Reactivity
    • 27
    • 24
    • 22
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 40
    • 2
    Rabbit
    Clonality
    • 42
    Polyclonal
    Conjugate
    • 18
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This BRE antibody is un-conjugated
    Application
    • 31
    • 13
    • 13
    • 12
    • 10
    • 8
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    Immunofluorescence (IF)
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human BRE (NP_954661.1).
    Isotype
    IgG
    Top Product
    Discover our top product BRE Primary Antibody
  • Application Notes
    IF 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    BRE (Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE))
    Alternative Name
    BRE (BRE Products)
    Synonyms
    brcc4 antibody, brcc45 antibody, BRE antibody, LOC100231620 antibody, BRCC4 antibody, BRCC45 antibody, 6030405P19Rik antibody, AI429776 antibody, B830038C02Rik antibody, im:7141046 antibody, zgc:110368 antibody, BRISC and BRCA1 A complex member 2 antibody, brain and reproductive organ-expressed (TNFRSF1A modulator) antibody, BRISC and BRCA1 A complex member 2 L homeolog antibody, babam2 antibody, BABAM2 antibody, Babam2 antibody, BRE antibody, babam2.L antibody
    Background
    This gene encodes an anti-apoptotic, death receptor-associated protein that interacts with tumor necrosis factor-receptor-1. The encoded protein acts as an adapter in several protein complexes, including the BRCA1-A complex and the BRISC complex. The BRCA1-A complex possesses ubiquitinase activity and targets sites of double strand DNA breaks, while the BRISC complex exhibits deubiquitinase activity and is involved in mitotic spindle assembly. This gene is upregulated in several types of cancer.
    Molecular Weight

    Observed_MW: 44kDa

    Calculated_MW: 42kDa/43kDa/46kDa

    Gene ID
    9577
    UniProt
    Q9NXR7
    Pathways
    Positive Regulation of Response to DNA Damage Stimulus
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