SNAP91 antibody

Catalog No. ABIN5967842

Product Details anti-SNAP91 Antibody

Target: SNAP91 (Synaptosomal-Associated Protein 91 (SNAP91))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNAP91 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human CALM2

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SNAP91

Target: SNAP91 (Synaptosomal-Associated Protein 91 (SNAP91))

Alternative Name: CALM (SNAP91 Products)

Synonyms: AP180 antibody, CALM antibody, Ap180 antibody, 91kDa antibody, F1-20 antibody, mKIAA0656 antibody, synaptosome associated protein 91 antibody, synaptosomal-associated protein, 91kDa homolog antibody, synaptosomal-associated protein 91 antibody, SNAP91 antibody, LOC100147907 antibody, Snap91 antibody

Background:

Synonyms: CALM 1,CALM 2,CALM 3,CALM,CALM,CALM1,CALM2,Calm3,CALML2,calmodulin 1 (phosphorylase kinase,delta),Calmodulin 2 (phosphorylase kinase,delta),Calmodulin 3 (phosphorylase kinase,delta),Calmodulin,CaM,CAM I,CAM1,CAM2,CAM3,CAMB,CAMC,CAMI,CAMII,CPVT4,DD132,FLJ99410,LP7057 protein,PHKD,PHKD2,PHKD3,phosphorylase kinase delta,phosphorylase kinase,delta subunit

Background: This gene is a member of the calmodulin gene family. There are three distinct calmodulin genes dispersed throughout the genome that encode the identical protein, but differ at the nucleotide level. Calmodulin is a calcium binding protein that plays a role in signaling pathways, cell cycle progression and proliferation. Several infants with severe forms of long-QT syndrome (LQTS) who displayed life-threatening ventricular arrhythmias together with delayed neurodevelopment and epilepsy were found to have mutations in either this gene or another member of the calmodulin gene family (PMID:23388215). Mutations in this gene have also been identified in patients with less severe forms of LQTS (PMID:24917665), while mutations in another calmodulin gene family member have been associated with catecholaminergic polymorphic ventricular tachycardia (CPVT)(PMID:23040497), a rare disorder thought to be the cause of a significant fraction of sudden cardiac deaths in young individuals. Pseudogenes of this gene are found on chromosomes 10, 13, and 17. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight:

Observed_MW: 15kDa

Calculated_MW: 17kDa

Gene ID: 801

UniProt: P62158