GRIN2B antibody (pTyr1474)

Catalog No. ABIN596833

This Rabbit Polyclonal antibody specifically detects GRIN2B in IF. It exhibits reactivity toward Human, Rat, Mouse, Dog, Cow, Zebrafish (Danio rerio), Pig, Monkey and Xenopus laevis.

Quick Overview for GRIN2B antibody (pTyr1474) (ABIN596833)

Target: GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))

Reactivity: Human, Rat, Mouse, Dog, Cow, Zebrafish (Danio rerio), Pig, Monkey, Xenopus laevis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRIN2B antibody is un-conjugated

Application: Immunofluorescence (IF)

Product Details anti-GRIN2B Antibody

Binding Specificity: pTyr1474

Specificity: Recognizes human NR2B when phosphorylated at tyrosine 1474. Species cross-reactivity: mouse, rat.

Purification: Immunoaffinity purified

Immunogen: Synthetic phosphopeptide corresponding to human NMDAR2B around the phosphorylation site of Tyr1474 (H-V-YP-E-K).

Type of Immunogen: Synthetic phospho-peptide

Isotype: IgG

Application Details

Application Notes: Approved: IF (1:100 - 1:200)

Usage: Suitable for use in Immunofluorescence: 1:100-1:200.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS (without Mg2+, Ca2+),  pH 7.4, 150 mM sodium chloride, 0.02 % sodium azide, 50 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Aliquot to Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: May be stored at 4°C for short-term only. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Aliquots are stable for at least 1 year.

Target Details for GRIN2B

Target: GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))

Alternative Name: GRIN2B / NMDAR2B / NR2B

Background: Name/Gene ID: GRIN2B
Subfamily: Glutamate receptor - ionotropic (NMDA receptor)
Family: Ion Channel

Synonyms: GRIN2B, GluN2B, GluR epsilon 2, NMDA receptor 2B, NMDAR2B, NR2B, NR3, MRD6, HNR3

Gene ID: 2904

UniProt: Q13224

Pathways: Response to Growth Hormone Stimulus, Synaptic Membrane, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity