Lamin A/C antibody (AA 451-468)

Catalog No. ABIN599839

This Rabbit Polyclonal antibody specifically detects Lamin A/C in WB, IHC and IHC (p). It exhibits reactivity toward Human, Mouse, Rat, Cow, Pig, Monkey, Rabbit, Horse and Hamster.

Quick Overview for Lamin A/C antibody (AA 451-468) (ABIN599839)

Target: Lamin A/C (LMNA)

Reactivity: Human, Mouse, Rat, Cow, Pig, Monkey, Rabbit, Horse, Hamster

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Lamin A/C antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Lamin A/C Antibody

Binding Specificity: AA 451-468

Specificity: Recognizes human Lamin A + C. Species cross-reactivity: mouse, rat.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Bovine, Horse, Rabbit, Pig (100%) Panda, Bat, Dog, Opossum (94%) Chicken, Xenopus (89%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide corresponding to aa 451-468, FVRLRNKSNEDQSMGNWQ to human Lamin A and Lamin C. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Bovine, Horse, Rabbit, Pig (100%), Panda, Bat, Dog, Opossum (94%), Chicken, Xenopus (89%).

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: IHC, IHC-P (1 - 2 μg/mL), WB (2 μg/mL)

Usage: Suitable for use in Western Blot and Immunohistochemistry. Western Blot: 2.0 μg/mL. Immunohistochemistry (Paraffin and Formalin): 1-2.0 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Sterile distilled water

Concentration: Lot specific

Buffer: Lyophilized from sodium phosphate, sodium chloride, 5 mg BSA, 0.05 mg Thimerosal, 0.05 mg sodium azide

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Aliquot to Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Lyophilized powder may be stored at -20°C. Stable for 1 year at -20°C. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Reconstituted product is stable for 1 year at -20°C.

Target Details for Lamin A/C

Target: Lamin A/C (LMNA)

Alternative Name: LMNA / Lamin A/C

Background: Name/Gene ID: LMNA

Synonyms: LMNA, 70 kDa lamin, CDCD1, CMD1A, EMD2, FPLD, IDC, FPL, FPLD2, Lamin A/C, Lamin, LFP, LMNC, LMN1, LMNL1, HGPS, Prelamin-A/C, PRO1, Lamin A, Lamin A/C-like 1, LGMD1B, CDDC, CMT2B1, LDP1

This antibody detects: LMNA / Lamin A+C

Gene ID: 4000

UniProt: P02545

Pathways: Apoptosis, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus