Aurora A antibody (pThr288)

Catalog No. ABIN600485

The Rabbit Polyclonal anti-Aurora A antibody has been validated for IHC. It is suitable to detect Aurora A in samples from Human and Monkey.

Quick Overview for Aurora A antibody (pThr288) (ABIN600485)

Target: Aurora A (AURKA) (Aurora Kinase A (AURKA))

Reactivity: Human, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Aurora A antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-Aurora A Antibody

Binding Specificity: pThr288

Specificity: Recognizes human AURKA when phosphorylated at Thr288. Species cross-Reactivity: mouse.

Purification: Immunoaffinity purified

Immunogen: Synthetic phosphopeptide corresponding to human AURKA around the phosphorylation site of threonine 288 (R-T-TP-L-M).

Type of Immunogen: Synthetic phospho-peptide

Isotype: IgG

Application Details

Application Notes: Approved: IHC (1:50 - 1:100)

Usage: Suitable for use in Immunohistochemistry:1:50-1:100.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS (without Mg2+, Ca2+),  pH 7.4, 150 mM sodium chloride, 0.02 % sodium azide, 50 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Aliquot to Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: May be stored at 4°C for short-term only. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Aliquots are stable for at least 1 year.

Target Details for Aurora A

Target: Aurora A (AURKA) (Aurora Kinase A (AURKA))

Alternative Name: AURKA / Aurora-A

Background: Name/Gene ID: AURKA
Subfamily: Aurora/IPL1-like
Family: Protein Kinase

Synonyms: AURKA, AIK, AIRK1, ARK1, Aurora-A kinase, Aurora kinase A, Aurora/IPL1-like kinase, AYK1, AURA, AURORA2, Breast tumor-amplified kinase, Breast-tumor-amplified kinase, BTAK, HARK1, IPL1-related kinase, Serine/threonine kinase 6, STK7, STK6, PPP1R47, ARK-1, Aurora 2, Aurora-A, Aurora-related kinase 1, Aurora/IPL1-related kinase 1, IAK1, Serine/threonine kinase 15, STK15

Gene ID: 6790

UniProt: O14965

Pathways: Cell Division Cycle, Asymmetric Protein Localization