CHEK1 antibody (pSer317)
Quick Overview for CHEK1 antibody (pSer317) (ABIN601007)
Target
See all CHEK1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- pSer317
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Specificity
- Recognizes human Chk1 when phosphorylated at serine 317. Species cross-Reactivity: rat.
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Purification
- Immunoaffinity purified
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Immunogen
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Synthetic phosphopeptide corresponding to human CHK1 around the phosphorylation site of serine 317 (S-S-SP-Q-P).
Type of Immunogen: Synthetic phospho-peptide -
Isotype
- IgG
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Application Notes
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Approved: ELISA (1:4000), IHC (1:50 - 1:100), WB (1:500 - 1:1000)
Usage: Suitable for use in ELISA, Western Blot, and Immunohistochemistry. ELISA:1:4000. Western Blot:1:500-1:1000. Immunohistochemistry:1:50-1:100. -
Comment
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02 % sodium azide, 50 % glycerol
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Aliquot to Avoid repeated freezing and thawing.
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Storage
- 4 °C,-20 °C
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Storage Comment
- May be stored at 4°C for short-term only. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Aliquots are stable for at least 1 year.
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- CHEK1 (Checkpoint Kinase 1 (CHEK1))
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Alternative Name
- CHEK1 / CHK1
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Background
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Name/Gene ID: CHEK1
Subfamily: NIM1
Family: Protein Kinase
Synonyms: CHEK1, CHK1 checkpoint homolog, Cell cycle checkpoint kinase, Checkpoint kinase 1, CHK1, Chk1-S, Protein kinase chk1, Checkpoint kinase-1 -
Gene ID
- 1111
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UniProt
- O14757
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Pathways
- p53 Signaling, Apoptosis, Cell Division Cycle, DNA Damage Repair
Target
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