MAP2K3 antibody

Catalog No. ABIN601849

This Rabbit Polyclonal antibody specifically detects MAP2K3 in WB, IHC and IF. It exhibits reactivity toward Human, Mouse, Rat, Dog, Monkey, Zebrafish (Danio rerio), Rabbit, Cow, Horse and Chicken.

Quick Overview for MAP2K3 antibody (ABIN601849)

Target: MAP2K3 (Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3))

Reactivity: Human, Mouse, Rat, Dog, Monkey, Zebrafish (Danio rerio), Rabbit, Cow, Horse, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP2K3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-MAP2K3 Antibody

Specificity: Recognizes human MAP Kinase Kinase 3. Species cross-reactivity: mouse.

Purification: Immunoaffinity purified

Immunogen: Synthetic non-phosphopeptide corresponding to human MKK3 around the phosphorylation site of serine 189 (V-D-SP-V-A).

Type of Immunogen: Synthetic Non-phosphopeptide

Isotype: IgG

Application Details

Application Notes: Approved: IF (1:100 - 1:200), IHC (1:50 - 1:100), WB (1:500 - 1:1000)

Usage: Suitable for use in Immunofluorescence, Western Blot, and Immunohistochemistry. Immunofluorescence: 1:100-1:200. Western Blot: 1:500-1:1000. Immunohistochemistry: 1:50-1:100.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS (without Mg2+, Ca2+),  pH 7.4, 150 mM sodium chloride, 0.02 % sodium azide, 50 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Aliquot to Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: May be stored at 4°C for short-term only. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Aliquots are stable for at least 1 year.

Target Details for MAP2K3

Target: MAP2K3 (Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3))

Alternative Name: MAP2K3 / MEK3 / MKK3

Background: Name/Gene ID: MAP2K3
Subfamily: MAP2K
Family: Protein Kinase

Synonyms: MAP2K3, MAPKK 3, MAPKK3, PRKMK3, SAPK kinase 2, SAPKK-2, SAPKK2, SKK2, MAP kinase kinase 3, MEK 3, MEK3, MKK3, MAPK/ERK kinase 3

Gene ID: 5606

UniProt: P46734

Pathways: MAPK Signaling, TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Autophagy, Signaling Events mediated by VEGFR1 and VEGFR2