TNF alpha antibody

Catalog No. ABIN603912

The Mouse Monoclonal anti-TNF alpha antibody (ABIN603912) specifically detects TNF alpha in ELISA and Neut. The antibody is reactive with Human, Dog, Cow and Monkey samples.

Quick Overview for TNF alpha antibody (ABIN603912)

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Reactivity: Human, Dog, Cow, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This TNF alpha antibody is un-conjugated

Application: ELISA, Neutralization (Neut)

Product Details anti-TNF alpha Antibody

Specificity: Recognizes human Tumor Necrosis Factor alpha (TNF-alpha). Cross-reacts and cross-neutralizes all monkey species TNF-alpha, except pig-tail macaque. With affinity about two orders lower it recognizes bovine and canine TNF-alpha.

Purification: Purified

Immunogen: Human TNF-alpha.

Type of Immunogen: Protein

Isotype: IgG2a

Application Details

Application Notes: Approved: ELISA, Neut

Usage: Suitable for use in ELISA and Neutralization. Recommended Dilutions. Kd= 5.7x10e-10M.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.1 % BSA

Handling Advice: Avoid repeated freezing and thawing

Storage: 4 °C,-20 °C

Storage Comment: May be stored at 4°C for short-term only. For long-term storage and to avoid freeze-thaw cycles, aliquot and store at -20°C. Aliquots are stable for at least 1 year at -20°C.

Target Details for TNF alpha

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Alternative Name: TNF Alpha

Background: Name/Gene ID: TNF
Family: TNF

Synonyms: TNF, APC1 protein, Cachectin, DIF, TNF Alpha, Tumor necrosis factor-alpha, TNF-alpha, TNF-a, TNFA, Tumor necrosis factor, TNF, macrophage-derived, TNF, monocyte-derived, TNFSF2

Gene ID: 7124

UniProt: P01375

Pathways: NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome