Tumor Necrosis Factor antibody (TNF) (PE)

Details for Product anti-TNF Antibody No. ABIN610452, Supplier: Log in to see
Antigen
  • DIF
  • TNF-alpha
  • TNFA
  • TNFSF2
  • RATTNF
  • Tnfa
  • tnf
  • TNF-a
  • TNFalpha
  • Tnfsf1a
  • TNFa
  • cTNF
  • Tnf-alpha
  • tnfa-like
  • TNF-ALPHA
  • dif
  • tnfa
  • xtnf
  • tnfsf2
  • tnf-alpha
  • Cachectin
  • tumor necrosis factor
  • tumor necrosis factor b (TNF superfamily, member 2)
  • tumor necrosis factor alpha
  • lipopolysaccharide induced TNF factor
  • tumor necrosis factor a (TNF superfamily, member 2)
  • TNF
  • Tnf
  • tnf
  • tnfb
  • tnf-alpha
  • LITAF
  • LOC103694380
  • tnfa
Alternatives
anti-Human Tumor Necrosis Factor antibody for ELISA
Reactivity
Human
1272
460
357
144
136
119
118
59
53
40
29
17
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Host
Mouse
943
529
178
48
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9
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2
Clonality (Clone)
Monoclonal ()
Conjugate
This Tumor Necrosis Factor antibody is conjugated to PE
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97
72
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13
9
4
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2
1
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Application
Functional Studies (Func), Flow Cytometry (FACS), Immunohistochemistry (IHC), Western Blotting (WB)
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619
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Options
Supplier
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Supplier Product No.
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Immunogen Recombinant human TNF alpha.

Type of Immunogen: Recombinant protein
Clone J1D9
Isotype IgG1
Specificity Human TNF alpha.
Purification Gel filtration
Alternative Name TNF Alpha (TNF Antibody Abstract)
Background Name/Gene ID: TNF
Family: TNF

Synonyms: TNF, APC1 protein, Cachectin, DIF, TNF Alpha, Tumor necrosis factor-alpha, TNF-alpha, TNF-a, TNFA, Tumor necrosis factor, TNF, macrophage-derived, TNF, monocyte-derived, TNFSF2
Gene ID 7124
UniProt P01375
Pathways NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus
Application Notes Approved: Flo, Func, IHC, WB

Usage: Function: Neutralizes TNF alpha biological activities. It prevents TNF alpha induced apoptosis in Jurkat cells. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Comment

Target Species of Antibody: Human

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer 50 mM sodium phosphate,  pH 7.5, 500 mM potassium chloride, 150 mM sodium chloride, 15 % Glycerol, 0.2 % BSA, 0.04 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Do not freeze. Product is photosensitive and should be protected from light.
Storage 4 °C
Storage Comment Store at 4°C. Do not freeze. Protect from light.
Product cited in: Duchene, Schanstra, Pecher, Pizard, Susini, Esteve, Bascands, Girolami: "A novel protein-protein interaction between a G protein-coupled receptor and the phosphatase SHP-2 is involved in bradykinin-induced inhibition of cell proliferation." in: The Journal of biological chemistry, Vol. 277, Issue 43, pp. 40375-83, 2002 (PubMed).

Xie, Browning, Hay, Mackman, Ye: "Activation of NF-kappa B by bradykinin through a Galpha(q)- and Gbeta gamma-dependent pathway that involves phosphoinositide 3-kinase and Akt." in: The Journal of biological chemistry, Vol. 275, Issue 32, pp. 24907-14, 2000 (PubMed).

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