CRY1 antibody (AA 507-586)

Catalog No. ABIN6139062

Product Details anti-CRY1 Antibody

Target: CRY1 (Cryptochrome 1 (Photolyase-Like) (CRY1))

Binding Specificity: AA 507-586

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRY1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: PNGNGGFMGY SAENIPGCSS SGSCSQGSGI LHYAHGDSQQ THLLKQGRSS MGTGLSGGKR PSQEEDTQSI GPKVQRQSTN

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 507-586 of human CRY1 (NP_004066.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CRY1

Target: CRY1 (Cryptochrome 1 (Photolyase-Like) (CRY1))

Alternative Name: CRY1 (CRY1 Products)

Synonyms: cry1-A antibody, CRY1 antibody, cry2 antibody, phll1 antibody, xCRY1 antibody, PHLL1 antibody, AU020726 antibody, AU021000 antibody, Phll1 antibody, ATCRY1 antibody, BLU1 antibody, BLUE LIGHT UNINHIBITED 1 antibody, CRYPTOCHROME 1 APOPROTEIN (BLUE LIGHT PHOTORECEPTOR antibody, ELONGATED HYPOCOTYL 4 antibody, HY4 antibody, OOP2 antibody, OUT OF PHASE 2 antibody, T3H13.14 antibody, T3H13_14 antibody, cryptochrome 1 antibody, cryptochrome circadian clock 1 L homeolog antibody, cryptochrome circadian regulator 1 antibody, cryptochrome circadian clock 1 antibody, Cryptochrome-1 antibody, cryptochrome 1 antibody, cryptochrome 1 (photolyase-like) antibody, cry1.L antibody, CRY1 antibody, cry1 antibody, siu50817b antibody, Cry1 antibody

Background: This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Loss of the related gene in mouse results in a shortened circadian cycle in complete darkness.,CRY1,PHLL1,DSPD,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Neuroscience,Cardiovascular,Blood,Blood Pressure regulation,CRY1

Molecular Weight: 66 kDa

Gene ID: 1407

UniProt: Q16526

Pathways: Response to Water Deprivation, Proton Transport