ATP6V1D antibody (AA 1-247)

Catalog No. ABIN6137348

Product Details anti-ATP6V1D Antibody

Target: ATP6V1D (ATPase, H+ Transporting, Lysosomal 34kDa, V1 Subunit D (ATP6V1D))

Binding Specificity: AA 1-247

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP6V1D antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: MSGKDRIEIF PSRMAQTIMK ARLKGAQTGR NLLKKKSDAL TLRFRQILKK IIETKMLMGE VMREAAFSLA EAKFTAGDFS TTVIQNVNKA QVKIRAKKDN VAGVTLPVFE HYHEGTDSYE LTGLARGGEQ LAKLKRNYAK AVELLVELAS LQTSFVTLDE AIKITNRRVN AIEHVIIPRI ERTLAYIITE LDEREREEFY RLKKIQEKKK ILKEKSEKDL EQRRAAGEVL EPANLLAEEK DEDLLFE

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-247 of human ATP6V1D (NP_057078.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ATP6V1D

Target: ATP6V1D (ATPase, H+ Transporting, Lysosomal 34kDa, V1 Subunit D (ATP6V1D))

Alternative Name: ATP6V1D (ATP6V1D Products)

Synonyms: ATP6M antibody, VATD antibody, VMA8 antibody, VHA36 antibody, 1110004P10Rik antibody, Atp6m antibody, Vma8 antibody, ATPase H+ transporting V1 subunit D antibody, ATPase, H+ transporting, lysosomal V1 subunit D antibody, H(+)-transporting V1 sector ATPase subunit D antibody, ATP6V1D antibody, Atp6v1d antibody, VMA8 antibody

Background: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes the V1 domain D subunit protein.,ATP6V1D,ATP6M,VATD,VMA8,ATP6V1D

Molecular Weight: 28 kDa

Gene ID: 51382

UniProt: Q9Y5K8

Pathways: Transition Metal Ion Homeostasis, Proton Transport