C1QB antibody (AA 104-253)

Catalog No. ABIN6137754

Product Details anti-C1QB Antibody

Target: C1QB (Complement Component 1, Q Subcomponent, B Chain (C1QB))

Binding Specificity: AA 104-253

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C1QB antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PGAPGPKGES GDYKATQKIA FSATRTINVP LRRDQTIRFD HVITNMNNNY EPRSGKFTCK VPGLYYFTYH ASSRGNLCVN LMRGRERAQK VVTFCDYAYN TFQVTTGGMV LKLEQGENVF LQATDKNSLL GMEGANSIFS GFLLFPDMEA

Cross-Reactivity: Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 104-253 of human C1QB (NP_000482.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for C1QB

Target: C1QB (Complement Component 1, Q Subcomponent, B Chain (C1QB))

Alternative Name: C1QB (C1QB Products)

Synonyms: complement C1q B chain antibody, complement component 1, q subcomponent, beta polypeptide antibody, C1QB antibody, C1qb antibody

Background: This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the B-chain polypeptide of human complement subcomponent C1q,C1QB,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,C1QB

Molecular Weight: 26 kDa

Gene ID: 713

UniProt: P02746

Pathways: Complement System