CHRNG antibody (AA 328-517)

Catalog No. ABIN6138600

Product Details anti-CHRNG Antibody

Target: CHRNG (Cholinergic Receptor, Nicotinic, gamma (CHRNG))

Binding Specificity: AA 328-517

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRNG antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: NVSLRSPHTH SMARGVRKVF LRLLPQLLRM HVRPLAPAAV QDTQSRLQNG SSGWSITTGE EVALCLPRSE LLFQQWQRQG LVAAALEKLE KGPELGLSQF CGSLKQAAPA IQACVEACNL IACARHQQSH FDNGNEEWFL VGRVLDRVCF LAMLSLFICG TAGIFLMAHY NRVPALPFPG DPRPYLPSPD

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 328-517 of human CHRNG (NP_005190.4).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CHRNG

Target: CHRNG (Cholinergic Receptor, Nicotinic, gamma (CHRNG))

Alternative Name: CHRNG (CHRNG Products)

Synonyms: ACHRG antibody, Achr-3 antibody, Acrg antibody, cholinergic receptor nicotinic gamma subunit antibody, cholinergic receptor, nicotinic gamma L homeolog antibody, cholinergic receptor, nicotinic, gamma antibody, cholinergic receptor, nicotinic gamma antibody, cholinergic receptor, nicotinic, gamma polypeptide antibody, CHRNG antibody, chrng.L antibody, Chrng antibody, chrng antibody

Background: The mammalian muscle-type acetylcholine receptor is a transmembrane pentameric glycoprotein with two alpha subunits, one beta, one delta, and one epsilon (in adult skeletal muscle) or gamma (in fetal and denervated muscle) subunit. This gene, which encodes the gamma subunit, is expressed prior to the thirty-third week of gestation in humans. The gamma subunit of the acetylcholine receptor plays a role in neuromuscular organogenesis and ligand binding and disruption of gamma subunit expression prevents the correct localization of the receptor in cell membranes. Mutations in this gene cause Escobar syndrome and a lethal form of multiple pterygium syndrome. Muscle-type acetylcholine receptor is the major antigen in the autoimmune disease myasthenia gravis.,CHRNG,ACHRG,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,CHRNG

Molecular Weight: 52 kDa/57 kDa

Gene ID: 1146

UniProt: P07510