CIDEA antibody (AA 20-219)

Catalog No. ABIN6138621

Product Details anti-CIDEA Antibody

Target: CIDEA (Cell Death-Inducing DFFA-Like Effector A (CIDEA))

Binding Specificity: AA 20-219

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CIDEA antibody is un-conjugated

Application: Immunofluorescence (IF)

Sequence: SQTKRVLFTP LMHPARPFRV SNHDRSSRRG VMASSLQELI SKTLDALVIA TGLVTLVLEE DGTVVDTEEF FQTLGDNTHF MILEKGQKWM PGSQHVPTCS PPKRSGIARV TFDLYRLNPK DFIGCLNVKA TMYEMYSVSY DIRCTGLKGL LRSLLRFLSY SAQVTGQFLI YLGTYMLRVL DDKEERPSLR SQAKGRFTCG

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-219 of human CIDEA (NP_001270.1).

Isotype: IgG

Application Details

Application Notes: IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CIDEA

Target: CIDEA (Cell Death-Inducing DFFA-Like Effector A (CIDEA))

Alternative Name: CIDEA (CIDEA Products)

Synonyms: CIDE-A antibody, AW212747 antibody, CIDEA antibody, cide-a antibody, MGC89985 antibody, cell death-inducing DFFA-like effector a antibody, cell death-inducing DNA fragmentation factor, alpha subunit-like effector A antibody, cell death-inducing DFFA-like effector a L homeolog antibody, CIDEA antibody, Cidea antibody, cidea antibody, cidea.L antibody

Background: This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified.,CIDEA,CIDE-A,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Endocrine & Metabolism,Cardiovascular,Heart,Lipids,Fatty Acids,CIDEA

Molecular Weight: 24 kDa

Gene ID: 1149

UniProt: O60543