HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd) (AA 16-250) antibody

Catalog No. ABIN6140300

Product Details

Target: HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd)

Binding Specificity: AA 16-250

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Sequence: AYRHPDFPLL EKAQQLLQST GSPYSTNCWL CTSSSTETPG TAYPASPREW TSIEAELHIS YRWDPNLKGL MRPANSLLST VKQDFPDIRQ KPPIFGPIFT NINLMGIAPI CVMAKRKNGT NVGTLPSTVC NVTFTVDSNQ QTYQTYTHNQ FRHQPRFPKP PNITFPQGTL LDKSSRFCQG RPSSCSTRNF WFRPADYNQC LQISNLSSTA EWVLLDQTRN SLFWENKTKG ANQSQ

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 16-250 of human ERVFRD-1 (NP_997465.1).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:4000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details

Target: HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd)

Alternative Name: ERVFRD-1 (Herv-frd Products)

Synonyms: ERVFRDE1 antibody, GLLL6191 antibody, HERV-FRD antibody, HERV-W/FRD antibody, UNQ6191 antibody, envFRD antibody, Gm52 antibody, Syna antibody, endogenous retrovirus group FRD member 1, envelope antibody, ERVFRD-1 antibody, Ervfrd-1 antibody

Target Type: Viral Protein

Background: Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of a human endogenous retrovirus provirus on chromosome 6 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product plays a major role in placental development and trophoblast fusion. The protein has the characteristics of a typical retroviral envelope protein, including a cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer.,ERVFRD-1,ERVFRDE1,GLLL6191,HERV-FRD,HERV-W/FRD,UNQ6191,envFRD,ERVFRD-1

Molecular Weight: 59 kDa

Gene ID: 405754

UniProt: P60508